Journal article

A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates.

Abstract:: A sweet solution: A strategy for the synthesis of well-defined carbohydrate-based vaccines is presented. The approach couples complex oligosaccharide synthesis to site-specific conjugation methodology to provide pure glycoprotein vaccine candidates (see scheme). Copyright © 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Share
Cite

Cite this record

APA Style

Grayson, E., Bernardes, G., Chalker, J., Boutureira, O., Koeppe, J. R., & Davis, B. (2011). A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates. Angewandte Chemie (International Ed. in English), 50(18), 4127–4132.

MLA Style

Grayson, E, et al. “A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates.” Angewandte Chemie (International Ed. in English), vol. 50, no. 18, 2011, pp. 4127–32.

Chicago Style

Grayson, E, G Bernardes, J Chalker, O Boutureira, JR Koeppe, and B Davis. 2011. “A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates.” Angewandte Chemie (International Ed. in English) 50 (18): 4127–32.
Print

Access Document

Publisher copy:: 10.1002/anie.201006327

Authors

+ Grayson, E More by this author

Role:: Author

+ Bernardes, G More by this author

Role:: Author

+ Chalker, J More by this author

Role:: Author

+ Boutureira, O More by this author

Role:: Author

+ Koeppe, JR More by this author

Role:: Author

More authors...

Journal:: Angewandte Chemie (International ed. in English) More from this journal
Volume:: 50
Issue:: 18
Pages:: 4127-4132
Publication date:: 2011-04-01
DOI:: 10.1002/anie.201006327
EISSN:: 1521-3773
ISSN:: 1433-7851

Language:: English
Keywords:: Subtilisins

Disulfides

Adjuvants, Immunologic

O Antigens

Oligosaccharides

Vaccines, Conjugate

Klebsiella pneumoniae

Structure-Activity Relationship

Glycoconjugates
Pubs id:: pubs:130915
UUID:: uuid:e88ca63e-0b9d-4241-aea8-3acccb5d96eb
Local pid:: pubs:130915
Source identifiers:: 130915
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_e88ca63e0b9d4241aea83acccb5d96eb

Terms of use

Copyright date:: 2011

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP