Journal article

Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis

Abstract:: Background
Previous meta-analyses of summary data from randomised controlled trials have shown that statin therapy increases the risk of diabetes, but less is known about the size or timing of this effect, or who is at greatest risk. We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double-blind trials of statin therapy.
Methods
We conducted a meta-analysis of individ... Expand abstract
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Reith, C. A., Preiss, D., Blackwell, L., Emberson, J., Davies, K., Halls, H., Harper, C., Holland, L., Wilson, K., Roddick, A., Clarke, R., Mihaylova, B., Armitage, J., Collins, R., Baigent, C., & Barnes, E. (2024). Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis. Lancet Diabetes and Endocrinology, 12(5), 306–319.

MLA Style

Reith, C. A., et al. “Effects of Statin Therapy on Diagnoses of New-Onset Diabetes and Worsening Glycaemia in Large-Scale Randomised Blinded Statin Trials: an Individual Participant Data Meta-Analysis.” Lancet Diabetes and Endocrinology, vol. 12, no. 5, Elsevier, 2024, pp. 306–19.

Chicago Style

Reith, CA, D Preiss, L Blackwell, J Emberson, K Davies, H Halls, C Harper, et al. 2024. “Effects of Statin Therapy on Diagnoses of New-Onset Diabetes and Worsening Glycaemia in Large-Scale Randomised Blinded Statin Trials: an Individual Participant Data Meta-Analysis.” Lancet Diabetes and Endocrinology 12 (5): 306–19.
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Files:: Reith_et_al_2024_Effects_of_statin.pdf

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Publisher copy:: 10.1016/s2213-8587(24)00040-8

Authors

+ Reith, CA More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Nuffield Department of Population Health
Sub department:: Clinical Trial Service Unit
Role:: Author

+ Preiss, D More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Nuffield Department of Population Health
Role:: Author
ORCID:: 0000-0003-3139-1836

+ Blackwell, L More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Nuffield Department of Population Health
Sub department:: Clinical Trial Service Unit
Role:: Author

+ Emberson, J More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Nuffield Department of Population Health
Sub department:: Clinical Trial Service Unit
Role:: Author
ORCID:: 0000-0001-7792-9422

+ Davies, K More by this author

Division:: MSD
Department:: Nuffield Department of Population Health
Sub department:: Clinical Trial Service Unit
Role:: Author
ORCID:: 0000-0001-6717-8354

More authors...

Contributors

+ Cholesterol Treatment Trialists’ (CTT) Collaboration

Role:: Contributor

+ British Heart Foundation More from this funder

Grant:: PG/18/16/33570

Publisher:: Elsevier
Journal:: Lancet Diabetes and Endocrinology More from this journal
Volume:: 12
Issue:: 5
Pages:: 306-319
Place of publication:: England
Publication date:: 2024-03-27
Acceptance date:: 2024-02-07
DOI:: 10.1016/s2213-8587(24)00040-8
EISSN:: 2213-8595
ISSN:: 2213-8587
Pmid:: 38554713

Language:: English
Keywords:: FFR
Pubs id:: 1929630
Local pid:: pubs:1929630
Deposit date:: 2024-04-23

Terms of use

Copyright holder:: Reith et al
Copyright date:: 2024
Rights statement:: © 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.

Licence:: CC Attribution (CC BY)

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