Journal article icon

Journal article

Homologous monoclonal antibodies specific for alpha 1-3 dextran stimulate polyclonal proliferation of Lyb-5+ B cells.

Abstract:

In this paper we describe the polyclonal blast response induced in nonimmune murine splenocytes by two homologous alpha 1-3 dextran-binding myeloma protein, J558 and MOPC104E. This stimulation appears to be independent of MHC or IgCh gene complex control, and proceeds entirely in a T-dependent fashion. The responding B cell population appears to belong to the more mature Lyb-5+ subset. This response was elicited by several independently prepared batches of J558 and MOPC104E, each of which was...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
134
Issue:
6
Pages:
3686-3692
Publication date:
1985-06-05
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:e87838a1-562c-48b1-aa89-9e033314fd81
Source identifiers:
28710
Local pid:
pubs:28710

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP