Prevalence and correlates of airflow obstruction in ∼317,000 never-smokers in China.

Journal article

In China, the burden of chronic obstructive disease (COPD) is high in never-smokers but little is known about its causes in this group. We analysed data on 287 000 female and 30 000 male never-smokers aged 30-79 years from 10 regions in China, who participated in the China Kadoorie Biobank baseline survey (2004-2008). Prevalence of airflow obstruction (AFO) (pre-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) <0.7 and below the lower limit of normal (LLN)) was estimated, by age and region. Cross-sectional associations of AFO (FEV1/FVC <0.7), adjusted for confounding, were examined. AFO prevalence defined as FEV1/FVC <0.7 was 4.0% in females and 5.1% in males (mean ages 51 and 54 years, respectively). AFO prevalence defined as FEV1/FVC

Authors: Smith, M; Li, L; Augustyn, M; Kurmi, O; Chen, J

• Publication status: Published
• Publisher: European Respiratory Society
• Journal: European respiratory journal
• Volume: 44
• Issue: 1
• Pages: 66-77
• Publication date: 2014-07-01
• DOI: 10.1183/09031936.00152413
• EISSN: 1399-3003
• ISSN: 0903-1936
• Language: English
• Keywords: China Kadoorie Biobank collaborative group