Journal article

Underestimation of the importance of homocysteine as a risk factor for cardiovascular disease in epidemiological studies.

Abstract:: BACKGROUND: In epidemiological studies, within-person variability in plasma total homocysteine (tHcy) measurements may dilute the association of 'usual' levels of tHcy with risk of cardiovascular disease, referred to as 'regression dilution'. The aim of this report was to estimate the magnitude of regression dilution after varying intervals of follow-up. METHODS: Regression dilution ratios (RDR) for tHcy were calculated using replicate tHcy measurements obtained after 3, 6 and 8 years from th...
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Publication status:: Published

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APA Style

Clarke, R., Lewington, S., Donald, A., Johnston, C., Refsum, H., Stratton, I., Jacques, P., Breteler, M., & Holman, R. (2001). Underestimation of the importance of homocysteine as a risk factor for cardiovascular disease in epidemiological studies. Journal of Cardiovascular Risk, 8(6), 363–369.

MLA Style

Clarke, R., et al. “Underestimation of the Importance of Homocysteine as a Risk Factor for Cardiovascular Disease in Epidemiological Studies.” Journal of Cardiovascular Risk, vol. 8, no. 6, 2001, pp. 363–69.

Chicago Style

Clarke, R, S Lewington, A Donald, C Johnston, H Refsum, I Stratton, P Jacques, M Breteler, and R Holman. 2001. “Underestimation of the Importance of Homocysteine as a Risk Factor for Cardiovascular Disease in Epidemiological Studies.” Journal of Cardiovascular Risk 8 (6): 363–69.
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Publisher copy:: 10.1097/00043798-200112000-00005

Authors

+ Clarke, R More by this author

Role:

Author

+ Lewington, S More by this author

Institution:

University of Oxford

Division:

MSD

Department:

Nuffield Department of Population Health

Sub department:

Clinical Trial Service Unit

Role:

Author

+ Donald, A More by this author

Role:

Author

+ Johnston, C More by this author

Role:

Author

+ Refsum, H More by this author

Role:

Author

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Bibliographic Details

Journal:: Journal of cardiovascular risk More from this journal
Volume:: 8
Issue:: 6
Pages:: 363-369
Publication date:: 2001-12-01
DOI:: 10.1097/00043798-200112000-00005
ISSN:: 1350-6277

Item Description

Language:: English
Keywords:: Female

Humans

Epidemiologic Studies

Diabetes Mellitus, Type 2

Homocysteine

Cardiovascular Diseases

Regression Analysis

Middle Aged

Male

Aged

Risk Assessment
Pubs id:: pubs:32062
UUID:: uuid:e841ecf2-6800-400c-9e56-f5f19301fd8e
Local pid:: pubs:32062
Source identifiers:: 32062
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2001

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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