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Journal article

A randomised, double-blind, controlled vaccine efficacy trial of DNA/MVA ME-TRAP against malaria infection in Gambian adults.

Abstract:

BACKGROUND: Many malaria vaccines are currently in development, although very few have been evaluated for efficacy in the field. Plasmodium falciparum multiple epitope (ME)- thrombospondin-related adhesion protein (TRAP) candidate vaccines are designed to potently induce effector T cells and so are a departure from earlier malaria vaccines evaluated in the field in terms of their mechanism of action. ME-TRAP vaccines encode a polyepitope string and the TRAP sporozoite antigen. Two vaccine ve...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pmed.0010033

Authors


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Institution:
University of Oxford
Imoukhuede, EB More by this author
Milligan, P More by this author
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Institution:
University of Oxford
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Med Journal website
Volume:
1
Issue:
2
Pages:
Article: e33
Publication date:
2004-11-05
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
URN:
uuid:e83ee315-704f-47e4-916f-7d13e34466c7
Source identifiers:
39391
Local pid:
pubs:39391

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