- Abstract:
-
BACKGROUND: The association between susceptibility to multiple sclerosis (MS) and HLA-DRB1*15 has been reported in various European populations. OBJECTIVE: To investigate the relationship between MS, HLA-DRB1*15 and other DRB1 alleles in a Portuguese population and their association with clinical course of MS. METHODS: The HLA-DRB1 alleles were analyzed by PCR-SSP in 248 MS patients and 282 healthy controls. In order to relate HLA-DRB1 alleles to disease aggressiveness, patients with relapsi...
Expand abstract - Publisher copy:
- 10.1016/j.jns.2007.02.033
-
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- Journal:
- Journal of the neurological sciences
- Volume:
- 258
- Issue:
- 1-2
- Pages:
- 69-74
- Publication date:
- 2007-07-05
- DOI:
- EISSN:
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1878-5883
- ISSN:
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0022-510X
- URN:
-
uuid:e825d058-1b2f-4832-8afe-229da74bd84c
- Source identifiers:
-
252275
- Local pid:
- pubs:252275
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
The role of HLA-DRB1 alleles on susceptibility and outcome of a Portuguese Multiple Sclerosis population.
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