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The role of HLA-DRB1 alleles on susceptibility and outcome of a Portuguese Multiple Sclerosis population.

Abstract:

BACKGROUND: The association between susceptibility to multiple sclerosis (MS) and HLA-DRB1*15 has been reported in various European populations. OBJECTIVE: To investigate the relationship between MS, HLA-DRB1*15 and other DRB1 alleles in a Portuguese population and their association with clinical course of MS. METHODS: The HLA-DRB1 alleles were analyzed by PCR-SSP in 248 MS patients and 282 healthy controls. In order to relate HLA-DRB1 alleles to disease aggressiveness, patients with relapsi...

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Publisher copy:
10.1016/j.jns.2007.02.033

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Journal:
Journal of the neurological sciences
Volume:
258
Issue:
1-2
Pages:
69-74
Publication date:
2007-07-05
DOI:
EISSN:
1878-5883
ISSN:
0022-510X
URN:
uuid:e825d058-1b2f-4832-8afe-229da74bd84c
Source identifiers:
252275
Local pid:
pubs:252275

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