Journal article

Synthesis of pyrrolidin-3-ones from dihydropyran precursors via spiro-N,O-acetals

Abstract:: 2,2-Disubstituted pyrrolidin-3-ones are prepared in three steps from simple dihydropyran derivatives; the key spiro-N,O-acetal intermediate is a useful N-sulfonylketoiminium ion precursor. This route represents a formal synthesis of the indolizidine alkaloid core, with potential application to pyrrolizidines and quinolizidines. © 2009 Elsevier Ltd. All rights reserved.

Publication status:: Published

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APA Style

Robertson, J., Tyrrell, A., Chovatia, P., & Skerratt, S. (2009). Synthesis of pyrrolidin-3-ones from dihydropyran precursors via spiro-N,O-acetals. TETRAHEDRON LETTERS, 50(51), 7141–7143.

MLA Style

Robertson, J., et al. “Synthesis of Pyrrolidin-3-Ones from Dihydropyran Precursors via Spiro-N,O-Acetals.” TETRAHEDRON LETTERS, vol. 50, no. 51, 2009, pp. 7141–43.

Chicago Style

Robertson, J, A Tyrrell, P Chovatia, and S Skerratt. 2009. “Synthesis of Pyrrolidin-3-Ones from Dihydropyran Precursors via Spiro-N,O-Acetals.” TETRAHEDRON LETTERS 50 (51): 7141–43.
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Publisher copy:: 10.1016/j.tetlet.2009.10.018

Authors

+ Robertson, J More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Tyrrell, A More by this author

Role:: Author

+ Chovatia, P More by this author

Role:: Author

+ Skerratt, S More by this author

Role:: Author

Journal:: TETRAHEDRON LETTERS More from this journal
Volume:: 50
Issue:: 51
Pages:: 7141-7143
Publication date:: 2009-12-23
DOI:: 10.1016/j.tetlet.2009.10.018
ISSN:: 0040-4039

Language:: English
Pubs id:: pubs:55214
UUID:: uuid:e80cc649-4c62-44bf-9e75-49179522322f
Local pid:: pubs:55214
Source identifiers:: 55214
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2009

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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