Adaptive optics in microscopy.

Journal article

Abstract:: The imaging properties of optical microscopes are often compromised by aberrations that reduce image resolution and contrast. Adaptive optics technology has been employed in various systems to correct these aberrations and restore performance. This has required various departures from the traditional adaptive optics schemes that are used in astronomy. This review discusses the sources of aberrations, their effects and their correction with adaptive optics, particularly in confocal and two-photon microscopes. Different methods of wavefront sensing, indirect aberration measurement and aberration correction devices are discussed. Applications of adaptive optics in the related areas of optical data storage, optical tweezers and micro/nanofabrication are also reviewed.

Journal:: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences More from this journal
Volume:: 365
Issue:: 1861
Pages:: 2829-2843
Publication date:: 2007-12-01
DOI:: 10.1098/rsta.2007.0013
EISSN:: 1471-2962
ISSN:: 1364-503X

Language:: English
Keywords:: Microscopy, Fluorescence, Multiphoton

Optics and Photonics

Optical Tweezers

Microscopy, Confocal

Image Enhancement

Equipment Design
Pubs id:: pubs:64391
UUID:: uuid:e793f721-75b8-42a7-abad-d30e11e554f2
Local pid:: pubs:64391
Source identifiers:: 64391
Deposit date:: 2013-11-16
ARK identifier:: ark:/29072/ora_e793f72175b842a7abadd30e11e554f2

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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