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Generalized binomial tau-leap method for biochemical kinetics incorporating both delay and intrinsic noise

Abstract:

The delay stochastic simulation algorithm (DSSA) by Barrio et al. [Plos Comput. Biol. 2, 117(E) (2006)] was developed to simulate delayed processes in cell biology in the presence of intrinsic noise, that is, when there are small-to-moderate numbers of certain key molecules present in a chemical reaction system. These delayed processes can faithfully represent complex interactions and mechanisms that imply a number of spatiotemporal processes often not explicitly modeled such as transcription...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1063/1.2919124

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
Publisher:
AIP Publishing
Journal:
Journal of Chemical Physics More from this journal
Volume:
128
Issue:
20
Pages:
205107
Publication date:
2008-05-30
Acceptance date:
2008-04-11
DOI:
EISSN:
1089-7690
ISSN:
0021-9606
Language:
English
Keywords:
UUID:
uuid:e77bdf99-dc41-424e-bf0b-96b67f957da0
Local pid:
pubs:291025
Source identifiers:
291025
Deposit date:
2012-12-19

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