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Journal article

The immunology of DNA vaccines.

Abstract:

The surprising observation that direct inoculation of an expression plasmid encoding a foreign protein into the skin of mice resulted in the induction of antibody responses, demonstrated that injection of "naked" DNA could result in antigen expression in an immunogenic form (1). This observation and the subsequent demonstration that intramuscular injections of plasmid DNA encoding influenza nucleoprotein could protect mice against a challenge with live influenza virus have opened up new avenu...

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Publisher copy:
10.1385/1-59259-688-6:37
Journal:
Methods in molecular medicine More from this journal
Volume:
29
Pages:
37-64
Publication date:
2000-01-01
DOI:
EISSN:
1940-6037
ISSN:
1543-1894
Language:
English
Pubs id:
pubs:222825
UUID:
uuid:e70c9e64-a7b6-460d-9790-f2e41e44b9ad
Local pid:
pubs:222825
Source identifiers:
222825
Deposit date:
2013-02-20

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