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Journal article

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

Abstract:

To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease. Mendelian randomisation meta-analysis of individual participant data from 47 epidemiological studies in 15 countries. 194418 participants, including 46557 patients with prevalent or incident coronary heart disease. Information was available on four CRP gene tagging single nucleotide polymorphisms (rs3093077, rs1205, rs1130864, rs1800947), concentration of C r...

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Publication status:
Published

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Publisher copy:
10.1136/bmj.d548

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Journal:
BRITISH MEDICAL JOURNAL
Volume:
342
Issue:
feb15 2
Pages:
d548-d548
Publication date:
2011-02-15
DOI:
EISSN:
1468-5833
ISSN:
0959-535X
URN:
uuid:e709a4c1-967b-4073-8223-ae1bf58309fe
Source identifiers:
120378
Local pid:
pubs:120378

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