Journal article

Severe Achromobacter xylosoxidans infection and loss of sputum bacterial diversity in an adult patient with cystic fibrosis

Abstract:: Achromobacter spp. are emerging pathogens in the lungs of patients with cystic fibrosis. We report the case of an adult patient with cystic fibrosis and chronic A. xylosoxidans infection who experienced rapid, progressive clinical deterioration. Metagenomic analysis of the sputum revealed that the airway microbiota was almost entirely dominated by A. xylosoxidans. We review the impact of this organism on lung function and the airway microbiome in cystic fibrosis, and discuss the potential for cross-infection between patients.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Talbot, N., & Flight, W. (2016). Severe Achromobacter xylosoxidans infection and loss of sputum bacterial diversity in an adult patient with cystic fibrosis. Paediatric Respiratory Reviews, 20(S), 27–29.

MLA Style

Talbot, N., and W. Flight. “Severe Achromobacter Xylosoxidans Infection and Loss of Sputum Bacterial Diversity in an Adult Patient with Cystic Fibrosis.” Paediatric Respiratory Reviews, vol. 20, no. S, Elsevier, 2016, pp. 27–29.

Chicago Style

Talbot, N, and W Flight. 2016. “Severe Achromobacter Xylosoxidans Infection and Loss of Sputum Bacterial Diversity in an Adult Patient with Cystic Fibrosis.” Paediatric Respiratory Reviews 20 (S): 27–29.
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Files:: Talbot & Flight Submitted Manuscript.pdf

(Preview, Accepted manuscript, pdf, 1.1MB, Terms of use)

Publisher copy:: 10.1016/j.prrv.2016.06.011

Authors

+ Talbot, N More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: NDM Strategic
Role:: Author

+ Flight, W More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Role:: Author

Publisher:: Elsevier
Journal:: Paediatric Respiratory Reviews More from this journal
Volume:: 20
Issue:: S
Pages:: 27-29
Publication date:: 2016-06-14
Acceptance date:: 2016-06-09
DOI:: 10.1016/j.prrv.2016.06.011
EISSN:: 1526-0550
ISSN:: 1526-0542

Keywords:: sputum microbiome

Achromobacter xylosoxidans

cross-infection

Cystic fibrosis
Pubs id:: pubs:628092
UUID:: uuid:e6d08361-d93d-4fa0-8403-30a924806e3b
Local pid:: pubs:628092
Source identifiers:: 628092
Deposit date:: 2016-06-16

Terms of use

Copyright holder:: Elsevier
Copyright date:: 2016
Notes:: © 2016 Published by Elsevier Ltd. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: [10.1016/j.prrv.2016.06.011]

Licence:: CC Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND)

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