Journal article
Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis.
- Abstract:
-
Reports of the use of HLA-B27/peptide tetrameric complexes to study peptide-specific CD8+ T cells in HLA-B27+-related diseases are rare. To establish HLA-B27 tetramers we first compared the function of HLA-B27 tetramers with HLA-A2 tetramers by using viral epitopes. HLA-B27 and HLA-A2 tetramers loaded with immunodominant peptides from Epstein-Barr virus were generated with comparable yields and both molecules detected antigen-specific CD8+ T cells. The application of HLA-B27 tetramers in HLA-...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 1.1MB, Terms of use)
-
- Publisher copy:
- 10.1186/ar1221
Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- Arthritis research and therapy More from this journal
- Volume:
- 6
- Issue:
- 6
- Pages:
- R521-R534
- Publication date:
- 2004-01-01
- DOI:
- EISSN:
-
1478-6362
- ISSN:
-
1478-6354
Item Description
- Language:
-
English
- Keywords:
-
- UUID:
-
uuid:e6bec1ef-8089-46c8-a49a-6b288d2668ee
- Local pid:
-
pubs:39320
- Source identifiers:
-
39320
- Deposit date:
-
2012-12-19
Terms of use
- Copyright holder:
- Appel et al
- Copyright date:
- 2004
- Notes:
- © 2004 Appel et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record