The control of Clostridium difficile infections (CDI) is an international clinical challenge. Uniquely, CDI incidence in England declined by ~80% after 2006, following implementation of national control policies; we investigated their role in this decline. This study tested two hypotheses. First, if CDI declines in England were driven by changes in use of particular antibiotics, then incidence of CDI caused by resistant isolates should decline faster than that caused by suscep...
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- Peer reviewed
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- G0800778; Health Protection Research Units on Healthcare Associated Infection and Antimicrobial Resistance (grant HPRU-2012-10041) and on Modelling Methodology (grant HPRU-2012-10080)
- Elsevier: Lancet Publisher's website
- Lancet Infectious Diseases Journal website
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- Copyright holder:
- Dingle et al.
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- © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license. Open access funded by Wellcome Trust.
Effects of control interventions on Clostridium difficile infection in England: an observational study
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