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The treatment of vulval lichen sclerosus with a very potent topical steroid (clobetasol propionate 0.05%) cream.

Abstract:

The clinical and histological response to 12 weeks of treatment with a very potent topical fluorinated steroid was studied in 15 patients with vulval lichen sclerosus (LS) who were treated with twice daily applications of clobetasol propionate 0.05% cream (Dermovate, Glaxo U.K.). Thirteen patients completed the study and all showed a marked clinical improvement. Histological measurements of skin biopsies taken before and after treatment showed a significant reduction in the characteristic fea...

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Publication status:
Published

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Authors


Dalziel, KL More by this author
Millard, PR More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Journal:
The British journal of dermatology
Volume:
124
Issue:
5
Pages:
461-464
Publication date:
1991-05-05
DOI:
EISSN:
1365-2133
ISSN:
0007-0963
URN:
uuid:e5071403-e614-4a4a-b089-9cb41fd3c2af
Source identifiers:
17613
Local pid:
pubs:17613

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