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A dual role for the lex2 locus: identification of galactosyltransferase activity in non-typeable Haemophilus influenzae strains 1124 and 2019.

Abstract:

Lipopolysaccharide (LPS) of Haemophilus influenzae comprises a conserved tri-l-glycero-d-manno-heptosyl inner-core moiety (l-alpha-d-Hepp-(1-->2)-[PEtn-->6]-l-alpha-d-Hepp-(1-->3)-[beta-d-GlcIp-(1-->4)]-l-alpha-d-Hepp-(1-->5)-alpha-Kdop) to which addition of beta-d-Glcp to O-4 of GlcI in serotype b strains is controlled by the gene lex2B. In non-typeable H. influenzae strains 1124 and 2019, however, a beta-d-Galp is linked to O-4 of GlcI. In order to test the hypothesis that th...

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Journal:
Carbohydrate research
Volume:
344
Issue:
5
Pages:
632-641
Publication date:
2009-03-05
DOI:
EISSN:
1873-426X
ISSN:
0008-6215
URN:
uuid:e4fdca05-ceb6-41e6-b259-1c847bae7e18
Source identifiers:
115640
Local pid:
pubs:115640

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