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Journal article

Effect of castration and castration with hormone replacement on the plasma prolactin responses to neuroendocrine challenge with i.v. mCPP in the male rat following a low tryptophan diet.

Abstract:

Previous studies have shown that castration increased brain 5-HT synthesis and that sex steroid hormone treatment can reverse this effect. Tryptophan (TRP) depletion has been shown to reduce brain 5-HT synthesis and to cause the post-synaptic 5-HT receptors to up-regulate. We have studied the effects of castration and hormone replacement on the prolactin responses to neuroendocrine challenge with the post-synaptic 5-HT agonist, m-chlorophenylpiperazine (m-CPP) in male rats on a low TRP diet. ...

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Publication status:
Published

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Publisher copy:
10.1177/026988119601000313

Authors


Franklin, M More by this author
Craven, RD More by this author
Journal:
Journal of psychopharmacology (Oxford, England)
Volume:
10
Issue:
3
Pages:
250-253
Publication date:
1996-01-05
DOI:
EISSN:
1461-7285
ISSN:
0269-8811
URN:
uuid:e4893b3a-66f6-47d5-bcc3-1632d303b0a3
Source identifiers:
186062
Local pid:
pubs:186062

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