Journal article icon

Journal article

Simulation studies of the interaction of antimicrobial peptides and lipid bilayers.

Abstract:

Experimental studies of a number of antimicrobial peptides are sufficiently detailed to allow computer simulations to make a significant contribution to understanding their mechanisms of action at an atomic level. In this review we focus on simulation studies of alamethicin, melittin, dermaseptin and related antimicrobial, membrane-active peptides. All of these peptides form amphipathic alpha-helices. Simulations allow us to explore the interactions of such peptides with lipid bilayers, and t...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


La Rocca, P More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Tieleman, DP More by this author
Sansom, MS More by this author
Journal:
Biochimica et biophysica acta
Volume:
1462
Issue:
1-2
Pages:
185-200
Publication date:
1999-12-05
DOI:
ISSN:
0006-3002
URN:
uuid:e45b92ec-c854-4aeb-a9ee-55159fcd8b8d
Source identifiers:
100697
Local pid:
pubs:100697

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP