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Identification of antigenic regions of duck hepatitis B virus core protein with antibodies elicited by DNA immunization and chronic infection.

Abstract:

The induction of humoral response in ducks by DNA-based immunization against duck hepatitis B virus (DHBV) core protein (DHBc) was investigated. In addition, the amino acid specificity of the induced response was compared by using peptide scanning to that elicited either by protein immunization or during chronic DHBV infection. Immunization of ducks with a plasmid expressing DHBc protein led to the induction of a long-lasting antibody response able to specifically recognize viral protein in c...

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Publication status:
Published

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Authors


Thermet, A More by this author
Robaczewska, M More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics, Clinical Medicine
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Journal:
Journal of virology
Volume:
78
Issue:
4
Pages:
1945-1953
Publication date:
2004-02-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:e4089fcd-cde3-483f-a773-013707c4c536
Source identifiers:
111461
Local pid:
pubs:111461

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