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Journal article

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue

Abstract:

Human leukocyte antigen (HLA)-B27 (B27) is the strongest genetic factor associated with development of Ankylosing Spondylitis and other spondyloarthropathies (SpA), yet the role it plays in disease pathogenesis remains unclear. We investigated the expression of potentially pathogenic non-conventional heavy chain forms (NC) of B27 in synovial and intestinal tissues obtained from SpA patients. We also determined the presence of NC-B27 in joints, lymphoid and gastrointestinal tissue from B27 tra...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jaut.2016.03.009

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Publisher:
Elsevier Publisher's website
Journal:
Journal of Autoimmunity Journal website
Volume:
70
Pages:
12-21
Publication date:
2016-03-29
Acceptance date:
2016-03-12
DOI:
EISSN:
1095-9157
ISSN:
0896-8411
Source identifiers:
613969
Language:
English
Keywords:
Pubs id:
pubs:613969
UUID:
uuid:e3e85df5-6b94-47dd-aeac-faff748e5d8f
Local pid:
info:fedora/pubs:613969
Deposit date:
2016-07-29

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