Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British Genetics of Hypertension Study.

Journal article

Human hypertension arises from a combination of genetic factors and lifestyle influences. With cardiovascular disease set to become the number 1 cause of death worldwide, it is important to understand the etiologic mechanisms for hypertension, because these might provide new routes to improved treatment. The British Genetics of Hypertension Study has recently published a primary genome screen that identified 4 chromosomal regions of interest. We have now genotyped additional markers to confir...

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Authors: Munroe, P; Wallace, C; Xue, M; Marçano, A; Dobson, R

• Publication status: Published
• Journal: Hypertension
• Volume: 48
• Issue: 1
• Pages: 105-111
• Publication date: 2006-07-01
• DOI: 10.1161/01.hyp.0000228324.74255.f1
• EISSN: 1524-4563
• ISSN: 0194-911X
• Language: English
• Keywords: Chromosome Mapping; Chromosomes, Human, Pair 5; Lod Score; Microsatellite Repeats; Humans; Great Britain; Siblings; Linkage Disequilibrium; Genotype; Medical Research Council British Genetics of Hypertension Study; Genetic Linkage; Hypertension