Journal article
Regulatory T cells reinforce intestinal homeostasis.
- Abstract:
-
Regulatory T cells help maintain intestinal homeostasis by preventing inappropriate innate and adaptive immune responses. CD4(+) T cells that express Foxp3 and Tr1-like cells that produce IL-10 comprise the major regulatory populations in the intestine. CD4(+)Foxp3(+) T cells play an important functional role in promoting tolerance of the flora and dietary proteins. Tr1-like cells can be generated in conditions that also promote effector T cell responses and may serve a similar function. In t...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.immuni.2009.08.011
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Authors
Bibliographic Details
- Journal:
- Immunity
- Volume:
- 31
- Issue:
- 3
- Pages:
- 401-411
- Publication date:
- 2009-09-01
- DOI:
- EISSN:
-
1097-4180
- ISSN:
-
1074-7613
- Source identifiers:
-
13704
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:13704
- UUID:
-
uuid:e2fa920c-1972-411a-9cc0-e15eb52d76ac
- Local pid:
- pubs:13704
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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