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Journal article

Regulatory T cells reinforce intestinal homeostasis.

Abstract:

Regulatory T cells help maintain intestinal homeostasis by preventing inappropriate innate and adaptive immune responses. CD4(+) T cells that express Foxp3 and Tr1-like cells that produce IL-10 comprise the major regulatory populations in the intestine. CD4(+)Foxp3(+) T cells play an important functional role in promoting tolerance of the flora and dietary proteins. Tr1-like cells can be generated in conditions that also promote effector T cell responses and may serve a similar function. In t...

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Publication status:
Published

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Journal:
Immunity
Volume:
31
Issue:
3
Pages:
401-411
Publication date:
2009-09-05
DOI:
EISSN:
1097-4180
ISSN:
1074-7613
URN:
uuid:e2fa920c-1972-411a-9cc0-e15eb52d76ac
Source identifiers:
13704
Local pid:
pubs:13704

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