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The evolution and maintenance of virulence in Staphylococcus aureus: a role for host-to-host transmission?

Abstract:

Despite progress in our understanding of infectious disease biology and prevention, the conditions that select for the establishment and maintenance of microbial virulence remain enigmatic. To address this aspect of pathogen biology, we focus on two members of the Staphylococcus genus - Staphylococcus aureus and Staphylococcus epidermidis - and consider why S. aureus has evolved to become more virulent than S. epidermidis. Several hypotheses to explain this phenomenon are discussed and a math...

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Publication status:
Published

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Publisher copy:
10.1038/nrmicro1551

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Journal:
Nature reviews. Microbiology
Volume:
4
Issue:
12
Pages:
953-958
Publication date:
2006-12-05
DOI:
EISSN:
1740-1534
ISSN:
1740-1526
URN:
uuid:e2f9ee5d-93d2-40fa-9c13-a85a51f64be8
Source identifiers:
209792
Local pid:
pubs:209792

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