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Journal article

Tumour subregion analysis of colorectal liver metastases using semi-automated clustering based on DCE-MRI: comparison with histological subregions and impact on pharmacokinetic parameter analysis

Abstract:

Purpose

To use a novel segmentation methodology based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to define tumour subregions of liver metastases from colorectal cancer (CRC), to compare these with histology, and to use these to compare extracted pharmacokinetic (PK) parameters between tumour subregions.

Materials and Methods

This ethically-approved prospective study recruited patients with CRC and ≥1 hepatic meta...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ejrad.2020.108934

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0002-8432-2511
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Publisher:
Elsevier Publisher's website
Journal:
European Journal of Radiology Journal website
Volume:
126
Article number:
108934
Publication date:
2020-03-06
Acceptance date:
2020-03-01
DOI:
EISSN:
1872-7727
ISSN:
0720-048X
Pmid:
32217426
Pubs id:
1097197
Local pid:
pubs:1097197
Language:
English
Keywords:
Format:
Print-Electronic

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