Journal article

Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability

Abstract:: Overall, our research provides the first direct evidence for a causal role of FLS in the genetic susceptibility for RA accounting for up to a quarter of RA heritability.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Ge, X., Frank-Bertoncelj, M., Klein, K., McGovern, A., Kuret, T., Houtman, M., Burja, B., Micheroli, R., Shi, C., Marks, M., Filer, A., Buckley, C. D., Orozco, G., Distler, O., Morris, A. P., Martin, P., Eyre, S., & Ospelt, C. (2021). Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability. Genome Biology, 22(1), 247–247.

MLA Style

Ge, X, et al. “Functional Genomics Atlas of Synovial Fibroblasts Defining Rheumatoid Arthritis Heritability.” Genome Biology, vol. 22, no. 1, 2021, pp. 247–47.

Chicago Style

Ge, X, M Frank-Bertoncelj, K Klein, et al. 2021. “Functional Genomics Atlas of Synovial Fibroblasts Defining Rheumatoid Arthritis Heritability.” Genome Biology 22 (1): 247–47.
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Files:: Ge_et_al_2021_Functional_genomics_atlas.pdf

(Preview, Version of record, pdf, 3.2MB, Terms of use)

Publisher copy:: 10.1186/s13059-021-02460-6

Authors

+ Ge, X More by this author

Role:: Author
ORCID:: 0000-0001-5048-8081

+ Frank-Bertoncelj, M More by this author

Role:: Author
ORCID:: 0000-0002-7257-2468

+ Klein, K More by this author

Role:: Author
ORCID:: 0000-0001-5303-8027

+ McGovern, A More by this author

Role:: Author
ORCID:: 0000-0001-7727-3283

+ Kuret, T More by this author

Role:: Author
ORCID:: 0000-0002-4749-594X

More authors...

+ Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung More from this funder

Funder identifier:: 10.13039/501100001711
Grant:: 320030_176061

+ Wellcome Trust More from this funder

Funder identifier:: 10.13039/100004440
Grant:: 207491/Z/17/Z

+ Versus Arthritis More from this funder

Funder identifier:: 10.13039/501100012041
Grant:: 21754

+ Manchester Biomedical Research Centre More from this funder

Funder identifier:: 10.13039/100014653

Publisher:: BioMed Central
Journal:: Genome Biology More from this journal
Volume:: 22
Issue:: 1
Pages:: 247-247
Article number:: 247
Publication date:: 2021-08-25
DOI:: 10.1186/s13059-021-02460-6
EISSN:: 1474-760X
ISSN:: 1474-7596

Language:: English
Keywords:: DNA methylation

Chromatin

Gene

Biology

Epigenome

Gene expression

Computational biology

Genome-wide association study

Enhancer

Genotype

Genetics

Single-nucleotide polymorphism

Epigenomics
Pubs id:: 1197875
Local pid:: pubs:1197875
Source identifiers:: W3194582202
Deposit date:: 2026-03-26
ARK identifier:: ark:/29072/ora_e20367b047b74fdcadcbab2d6f14e32a

Terms of use

Copyright date:: 2021

Licence:: CC Attribution (CC BY)

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