Journal article

A mass spectrometry-based hybrid method for structural modeling of protein complexes

Abstract:: We describe a method that integrates data derived from different mass spectrometry (MS)-based techniques with a modeling strategy for structural characterization of protein assemblies. We encoded structural data derived from native MS, bottom-up proteomics, ion mobility-MS and chemical cross-linking MS into modeling restraints to compute the most likely structure of a protein assembly. We used the method to generate near-native models for three known structures and characterized an assembly i...
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APA Style

Politis, A., Stengel, F., Hall, Z., Hernández, H., Leitner, A., Walzthoeni, T., Robinson, C., & Aebersold, R. (2014). A mass spectrometry-based hybrid method for structural modeling of protein complexes. Nature Methods, 11(4), 403–406.

MLA Style

Politis, A., et al. “A Mass Spectrometry-Based Hybrid Method for Structural Modeling of Protein Complexes.” Nature Methods, vol. 11, no. 4, Nature Publishing Group, 2014, pp. 403–06.

Chicago Style

Politis, A, F Stengel, Z Hall, H Hernández, A Leitner, T Walzthoeni, C Robinson, and R Aebersold. 2014. “A Mass Spectrometry-Based Hybrid Method for Structural Modeling of Protein Complexes.” Nature Methods 11 (4): 403–6.
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Publisher copy:: 10.1038/nmeth.2841

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+ Politis, A More by this author

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+ Stengel, F More by this author

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+ Hall, Z More by this author

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+ Hernández, H More by this author

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+ Leitner, A More by this author

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Bibliographic Details

Publisher:: Nature Publishing Group
Journal:: Nature Methods More from this journal
Volume:: 11
Issue:: 4
Pages:: 403-406
Publication date:: 2014-01-01
DOI:: 10.1038/nmeth.2841
EISSN:: 1548-7105
ISSN:: 1548-7091

Item Description

Language:: English
Pubs id:: pubs:462588
UUID:: uuid:e1f7cc6b-3451-4a21-be0f-8a8bc3f537bc
Local pid:: pubs:462588
Source identifiers:: 462588
Deposit date:: 2014-06-17

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Copyright date:: 2014

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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