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Investigation of DNA repair pathway activity.

Abstract:

DNA is constantly being damaged from endogenous and exogenous sources and efficient repair of different types of DNA lesions is essential for the survival of the organism. Dictyostelium is highly resistant to DNA damage and its genome sequence has revealed the presence of multiple repair pathways conserved with vertebrates but lost in other genetically tractable invertebrate models. As such, Dictyostelium is a powerful model organism to study selected human DNA repair pathways and may provide...

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
983
Pages:
295-310
Publication date:
2013
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
URN:
uuid:e1ed8ebb-ba04-4884-ad58-1754fea897b4
Source identifiers:
390857
Local pid:
pubs:390857

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