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Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment.

Abstract:

Specific language impairment (SLI) is a neurodevelopmental disorder that affects linguistic abilities when development is otherwise normal. We report the results of a genome-wide association study of SLI which included parent-of-origin effects and child genotype effects and used 278 families of language-impaired children. The child genotype effects analysis did not identify significant associations. We found genome-wide significant paternal parent-of-origin effects on chromosome 14q12 (P = 3....

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Publication status:
Published

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Publisher copy:
10.1111/gbb.12127

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Publisher:
Blackwell Publishing Ltd
Journal:
Genes, brain, and behavior
Volume:
13
Issue:
4
Pages:
418-429
Publication date:
2014-04-05
DOI:
EISSN:
1601-183X
ISSN:
1601-1848
URN:
uuid:e1e9ece2-a3ad-4f25-afe2-40c0950388e9
Source identifiers:
450927
Local pid:
pubs:450927

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