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Predicting the need for third-line antiretroviral therapy by identifying patients at high risk for failing second-line antiretroviral therapy in South Africa

Abstract:

Although third-line antiretroviral therapy (ART) is available in South Africa’s public sector, its cost is substantially higher than first and second line. Identifying risk factors for failure on second-line treatment remains crucial to reduce the need for third-line drugs. We conducted a case–control study including 194 adult patients (‡18 years; 70 cases and 124 controls) who initiated second-line ART in Johannesburg, South Africa. Unconditional logistic regression was used to assess predic...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1089/apc.2016.0291

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
van den Berg, L More by this author
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South African National and Gauteng provincial Department of Health More from this funder
United States Agency for International Development More from this funder
Publisher:
Mary Ann Liebert publishers Publisher's website
Journal:
AIDS Patient Care and STDs Journal website
Volume:
31
Issue:
5
Pages:
205-212
Publication date:
2017-05-01
DOI:
EISSN:
1557-7449
ISSN:
1087-2914
Pubs id:
pubs:853641
URN:
uri:e1ced5b6-d036-42f0-af92-dd7527b11392
UUID:
uuid:e1ced5b6-d036-42f0-af92-dd7527b11392
Local pid:
pubs:853641

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