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Journal article

Endemic scrub typhus in South America

Abstract:
Scrub typhus is a life-threatening zoonosis caused by Orientia tsutsugamushi organisms that are transmitted by the larvae of trombiculid mites. Endemic scrub typhus was originally thought to be confined to the so called "tsutsugamushi triangle" within the Asia-Pacific region. In 2006, however, two individual cases were detected in the Middle East and South America, which suggested that the pathogen was present farther afield. Here, we report three autochthonous cases of scrub typhus caused by O. tsutsugamushi acquired on Chiloé Island in southern Chile, which suggests the existence of an endemic focus in South America.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1056/NEJMoa1603657

Authors



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Grant:
totheMahidol–Oxford TropicalMedicineResearchUnit
theLao-Oxford-Mahoset Hospital–WellcomeTrustResearchUnit


Publisher:
Massachusetts Medical Society
Journal:
New England Journal of Medicine More from this journal
Volume:
375
Issue:
10
Pages:
954-961
Publication date:
2016-09-01
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Pmid:
27602667


Language:
English
Keywords:
Pubs id:
pubs:642232
UUID:
uuid:e18cb52f-6b66-4d56-997e-3537952bb203
Local pid:
pubs:642232
Source identifiers:
642232
Deposit date:
2016-10-06

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