Journal article icon

Journal article

Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells

Abstract:

Planarian flatworms have an indefinite capacity to regenerate missing or damaged body parts owing to a population of pluripotent adult stems cells called neoblasts (NBs). Currently, little is known about the importance of the epigenetic status of NBs and how histone modifications regulate homeostasis and cellular differentiation. We have developed an improved and optimized ChIP-seq protocol for NBs in Schmidtea mediterranea and have generated genome-wide profiles for the active marks H3K4me3 ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1101/gr.239848.118

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
Mihaylova, Y More by this author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
Expand authors...
Publisher:
Cold Spring Harbor Laboratory Press Publisher's website
Journal:
Genome Research Journal website
Volume:
28
Issue:
10
Pages:
1543-1554
Publication date:
2018-08-24
Acceptance date:
2018-08-16
DOI:
EISSN:
1549-5469
ISSN:
1088-9051
Pubs id:
pubs:911250
URN:
uri:e134078f-24b1-4afe-84a7-28a268ddaac6
UUID:
uuid:e134078f-24b1-4afe-84a7-28a268ddaac6
Local pid:
pubs:911250
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP