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Effects of empagliflozin on progression of chronic kidney disease: a prespecified secondary analysis from the empa-kidney trial

Abstract:

Background Sodium–glucose co-transporter-2 (SGLT2) inhibitors reduce progression of chronic kidney disease and the risk of cardiovascular morbidity and mortality in a wide range of patients. However, their effects on kidney disease progression in some patients with chronic kidney disease are unclear because few clinical kidney outcomes occurred among such patients in the completed trials. In particular, some guidelines stratify their level of recommendation about who shoul...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/S2213-8587(23)00321-2

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0002-1179-0023


Publisher:
Elsevier
Journal:
Lancet Diabetes and Endocrinology More from this journal
Volume:
12
Issue:
1
Pages:
39-50
Publication date:
2023-12-04
Acceptance date:
2023-10-25
DOI:
EISSN:
2213-8595
ISSN:
2213-8587


Language:
English
Keywords:
Pubs id:
1552533
Local pid:
pubs:1552533
Deposit date:
2023-10-25

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