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Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylate

Abstract:
Triazole-carboxylic acids related to D-glucose and D-galactose may be prepared by intramolecular [1,3]-dipolar cycloadditions of azides to unsaturated esters, followed by bromine oxidation of the resulting triazoline. Such materials may provide a series of anionic mimics of carbohydrates.
Publication status:
Published

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Publisher copy:
10.1016/S0957-4166(97)00561-2

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Journal:
TETRAHEDRON-ASYMMETRY More from this journal
Volume:
8
Issue:
22
Pages:
3807-3820
Publication date:
1997-11-27
DOI:
ISSN:
0957-4166


Language:
English
Pubs id:
pubs:45724
UUID:
uuid:e0867e6f-ce98-47b5-a6a7-b9c632f6e881
Local pid:
pubs:45724
Source identifiers:
45724
Deposit date:
2012-12-19

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