Journal article
Glucose homeostasis in mice is transglutaminase 2 independent
- Abstract:
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Transglutaminase type 2 (TG2) has been reported to be a candidate gene for maturity onset diabetes of the young (MODY) because three different mutations that impair TG2 transamidase activity have been found in 3 families with MODY. TG2 null (TG2(-/-)) mice have been reported to be glucose intolerant and have impaired glucose-stimulated insulin secretion (GSIS). Here we rigorously evaluated the role of TG2 in glucose metabolism using independently generated murine models of genetic TG2 disrupt...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.0MB)
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- Publisher copy:
- 10.1371/journal.pone.0063346
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Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Volume:
- 8
- Issue:
- 5
- Pages:
- e63346
- Publication date:
- 2013-05-22
- Acceptance date:
- 2013-03-29
- DOI:
- EISSN:
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1932-6203
- Source identifiers:
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402276
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:402276
- UUID:
-
uuid:e02653ac-842c-416e-bc35-d974cb435d9f
- Local pid:
- pubs:402276
- Deposit date:
- 2013-11-16
Terms of use
- Copyright holder:
- Iismaa et al
- Copyright date:
- 2013
- Notes:
- © 2013 Iismaa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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