Severe hypoglycemia and hyperinsulinemia in falciparum malaria.

Journal article

We studied the occurrence, clinical manifestations, and mechanism of hypoglycemia in patients with falciparum malaria in eastern Thailand. Hypoglycemia, which was often severe and recurrent, occurred in 17 patients, including 12 in a series of 151 patients with cerebral malaria. Thirty episodes were investigated. Plasma concentrations of insulin and C peptide were inappropriately high, and lactate and alanine concentrations were significantly higher than in patients with falciparum malaria wh...

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Authors: White, N; Warrell, D; Chanthavanich, P; Looareesuwan, S; Warrell, M

• Publication status: Published
• Journal: New England journal of medicine
• Volume: 309
• Issue: 2
• Pages: 61-66
• Publication date: 1983-07-01
• DOI: 10.1056/nejm198307143090201
• EISSN: 1533-4406
• ISSN: 0028-4793
• Language: English
• Keywords: Adolescent; Insulin; C-Peptide; Humans; Quinine; Malaria; Pregnancy Complications, Infectious; Female; Lactic Acid; Male; Brain Diseases; Hypoglycemia; Alanine; Child; 3-Hydroxybutyric Acid; Lactates; Pregnancy; Hydroxybutyrates; Adult; Blood Glucose; Plasmodium falciparum