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Immunization of HIV-infected adults in the UK with Haemophilus influenzae b/meningococcal C glycoconjugate and pneumococcal polysaccharide vaccines

Abstract:

U.K. guidelines for vaccinating HIV-infected adults against bacteria are based on limited data. We compared antibody responses between 211 HIV-infected and 73 HIV-uninfected adults vaccinated with pneumococcal polysaccharide vaccine (PPV) and Haemophilus influenzae b/meningococcal C polysaccharide-tetanus toxoid glycoconjugate vaccine (Hib/MenC-TT). IgG responses to Hib/MenC-TT were not significantly different. PPV induced median IgGs >1.3 μg/mL for 10/12 serotypes among HIV-uninfected par...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1097/QAI.0000000000001054

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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
Role:
Author
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Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
Journal of Acquired Immune Deficiency Syndromes Journal website
Volume:
73
Issue:
3
Pages:
287–293
Publication date:
2016-11-01
Acceptance date:
2016-04-04
DOI:
EISSN:
1944-7884
ISSN:
1525-4135
URN:
uuid:dfebadf6-8b64-470b-94e0-d7f532912d2e
Source identifiers:
623260
Local pid:
pubs:623260

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