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Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Abstract:

Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Al...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0094661

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Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
9
Issue:
6
Pages:
e94661
Publication date:
2014-06-12
Acceptance date:
2014-03-17
DOI:
EISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:469411
UUID:
uuid:dfe4a492-2fda-4202-93c9-bc27a5193528
Local pid:
pubs:469411
Source identifiers:
469411
Deposit date:
2014-06-17

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