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Journal article

Multiple sclerosis susceptibility and the X chromosome.

Abstract:

Multiple sclerosis (MS) is a chronic autoimmune complex trait with strong evidence for a genetic component. A female gender bias is clear but unexplained and a maternal parent-of-origin effect has been described. X-linked transmission of susceptibility has been previously proposed, based on pedigree, association and linkage studies. We genotyped 726 relative pairs including 552 affected sib-pairs for 22 X-chromosome microsatellite markers and a novel dataset of 195 aunt-uncle/niece-nephew (AU...

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Publication status:
Published

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Publisher copy:
10.1177/1352458507076961

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
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Journal:
Multiple sclerosis (Houndmills, Basingstoke, England)
Volume:
13
Issue:
7
Pages:
856-864
Publication date:
2007-08-01
DOI:
EISSN:
1477-0970
ISSN:
1352-4585
Source identifiers:
40480
Language:
English
Keywords:
Pubs id:
pubs:40480
UUID:
uuid:dfdb84e3-9824-49b0-9106-0e2546da68e1
Local pid:
pubs:40480
Deposit date:
2012-12-19

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