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Journal article

Responder analysis for pain relief and numbers needed to treat in a meta-analysis of etoricoxib osteoarthritis trials: bridging a gap between clinical trials and clinical practice.

Abstract:

BACKGROUND: Population mean changes from clinical trials are difficult to apply to individuals in clinical practice. Responder analysis may be better, but needs validating for level of response and treatment duration. METHODS: The numbers of patients with pain relief over baseline (> or =15%, > or =30%, > or =50%, > or =70%) at 2, 4, 8 and 12 weeks of treatment were obtained using the WOMAC 100 mm visual analogue pain subscale score for each treatment group in seven randomised pl...

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Publication status:
Published

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Publisher copy:
10.1136/ard.2009.107805

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Annals of the rheumatic diseases
Volume:
69
Issue:
2
Pages:
374-379
Publication date:
2010-02-05
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
URN:
uuid:dfc795e5-c7ac-4ca7-ba4b-0a48531234c4
Source identifiers:
241223
Local pid:
pubs:241223

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