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Radiotherapy to regional nodes in early breast cancer: individual-patient-data meta-analysis of 14,324 women in 16 trials

Abstract:

Background

Radiotherapy has become much better targeted since the 1980s, improving both safety and efficacy. In breast cancer, radiotherapy to regional lymph nodes aims to reduce risks of recurrence and death. Its effects have been studied in randomised trials, some before the 1980s and some after. We aimed to assess the effects of regional node radiotherapy in these two eras.

Methods

In this meta-analysis of individual patient da...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0140-6736(23)01082-6

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author

Contributors



Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
402
Issue:
10416
Pages:
1991-2003
Publication date:
2023-11-03
Acceptance date:
2023-04-28
DOI:
EISSN:
1474-547X
ISSN:
0140-6736


Language:
English
Keywords:
Pubs id:
1339482
Local pid:
pubs:1339482
Deposit date:
2023-05-02
ARK identifier:

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