First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials

Wasan, H; Gibbs, P; Sharma, N; Taieb, J; Heinemann, V; Ricke, J; Peeters, M; Findla, M; Weaver, A; Mills, J; Wilson, C; Adams, R; Francis, A; Moschandreas, J; Virdee, P; Dutton, P; Love, S; Gebski, V; Gray, A; FOXFIRE trial investigators; SIRFLOX trial investigators; FOXFIRE-Global trial investigators; van Hazel, G; Sharma, R

Journal article

First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials

Abstract:: Background Data suggest selective internal radiotherapy (SIRT) in third-line or subsequent therapy for metastatic colorectal cancer has clinical benefit in patients with colorectal liver metastases with liver-dominant disease after chemotherapy. The FOXFIRE, SIRFLOX, and FOXFIRE-Global randomised studies evaluated the efficacy of combining first-line chemotherapy with SIRT using yttrium-90 resin microspheres in patients with metastatic colorectal cancer with liver metastases.... Expand abstract
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Wasan, H., Gibbs, P., Sharma, N., Taieb, J., Heinemann, V., Ricke, J., Peeters, M., Findla, M., Weaver, A., Mills, J., Wilson, C., Adams, R., Francis, A., Moschandreas, J., Virdee, P., Dutton, P., Love, S., Gebski, V., Gray, A., … Sharma, R. (2017). First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials. Lancet Oncology, 18(9), 1159–1171.

MLA Style

Wasan, H, et al. “First-Line Selective Internal Radiotherapy plus Chemotherapy versus Chemotherapy Alone in Patients with Liver Metastases from Colorectal Cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a Combined Analysis of Three Multicentre, Randomised, Phase 3 Trials.” Lancet Oncology, vol. 18, no. 9, 2017, pp. 1159–71.

Chicago Style

Wasan, H, P Gibbs, N Sharma, et al. 2017. “First-Line Selective Internal Radiotherapy plus Chemotherapy versus Chemotherapy Alone in Patients with Liver Metastases from Colorectal Cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a Combined Analysis of Three Multicentre, Randomised, Phase 3 Trials.” Lancet Oncology 18 (9): 1159–71.
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