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Evidence for a peptidoglycan-like structure in Orientia tsutsugamushi.

Abstract:

Bacterial cell walls are composed of the large cross-linked macromolecule peptidoglycan, which maintains cell shape and is responsible for resisting osmotic stresses. This is a highly conserved structure and the target of numerous antibiotics. Obligate intracellular bacteria are an unusual group of organisms that have evolved to replicate exclusively within the cytoplasm or vacuole of a eukaryotic cell. They tend to have reduced amounts of peptidoglycan, likely due to the fact that their grow...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1111/mmi.13709

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine
Giengkam, S More by this author
Chaemchuen, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Kosaisawe, N More by this author
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Funding agency for:
Salje, J
Wellcome Trust More from this funder
Publisher:
Wiley Publisher's website
Journal:
Molecular Microbiology Journal website
Publication date:
2017-05-17
Acceptance date:
2017-05-14
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
Pubs id:
pubs:695783
URN:
uri:df28e3c0-5ae4-4081-81f9-247615547e03
UUID:
uuid:df28e3c0-5ae4-4081-81f9-247615547e03
Local pid:
pubs:695783
Language:
English
Keywords:

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