SARS-CoV-2 escape from cytotoxic T cells during long-term COVID-19

Journal article

Here, the authors report accelerated intrahost evolution of SARS-CoV-2 in an immunocompromised patient with non-Hodgkin’s lymphoma with 318 days long COVID-19, and show that changes in the viral genome resulted in escape from T cellular immune response

Authors: Stanevich, OV; Alekseeva, EI; Sergeeva, M; Fadeev, AV; Komissarova, KS

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Nature Research
• Journal: Nature Communications
• Volume: 14
• Issue: 1
• Pages: 149-149
• Article number: 149
• Publication date: 2023-01-10
• Acceptance date: 2022-10-11
• DOI: 10.1038/s41467-022-34033-x
• EISSN: 2041-1723
• ISSN: 2041-1723
• Language: English
• Keywords: Effector; Antigen; Virology; Disease; Biology; Genetics; Immunity; Immunology; Coronavirus disease 2019 (COVID-19); Immune escape; Antibody; Infectious disease (medical specialty); Medicine; Immune system; CD8; Cytotoxic T cell; Human leukocyte antigen