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Self-rated health status and risk of ischemic heart disease in the China Kadoorie Biobank study: a population based cohort study

Abstract:
Background: Self-rated health (SRH) is a strong predictor of mortality in different populations. However, the associations between SRH measures and risk of ischemic heart disease (IHD) have not been extensively explored, especially in Chinese population. Methods and Results: Over 0.5 million adults from 10 cities of China were followed from baseline (2004-2008) until 31 December 2013. Global SRH and age-comparative SRH were inquired in baseline questionnaires. Incident IHD cases were identified through linkage to well-established disease registry systems and national health insurance system. During 3,423,542 person-years of follow-up, we identified 24,705 incident cases of IHD. In multivariable-adjusted models, both SRH and age-comparative SRH were significantly associated with incident IHD. Compared with excellent SRH, the HRs (95% CIs) of good, fair, and poor SRH were 1.02 (0.98-1.07), 1.32 (1.27-1.37), and 1.76 (1.68-1.85), respectively. Compared with better age-comparative SRH, the HRs (95% CIs) of same and worse age-comparative SRH were 1.23 (1.19-1.27) and 1.78 (1.70-1.86), respectively. The associations persisted in all subgroup analyses, though slightly modified by study location, education and income levels. Conclusions: A simple question of self-assessment of health status was significantly associated with incident IHD in Chinese adults. Individuals and healthcare providers can use SRH measures as a convenient measure to assess future IHD risk.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/JAHA.117.006595

Authors


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Grant:
202922/Z/16/Z, 088158/Z/09/Z, 104085/Z/14/Z
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Grant:
2016YFC0900500,2016YFC0900501,2016YFC0900504,2017YFC0907500
2017YFC0907504
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Grant:
81390540,81390541,81390542,81202266,
81230069


Publisher:
American Heart Association
Journal:
Journal of the American Heart Association More from this journal
Volume:
6
Issue:
9
Article number:
e006595
Publication date:
2017-09-22
Acceptance date:
2017-08-16
DOI:
ISSN:
2047-9980


Keywords:
Pubs id:
pubs:724449
UUID:
uuid:debff737-9f42-45e5-b768-37078fd19503
Local pid:
pubs:724449
Source identifiers:
724449
Deposit date:
2017-08-29
ARK identifier:

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