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Journal article : Review

The effects of radiation therapy on the macrophage response in cancer

Abstract:

The efficacy of radiotherapy, a mainstay of cancer treatment, is strongly influenced by both cellular and non-cellular features of the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) are a heterogeneous population within the TME and their prevalence significantly correlates with patient prognosis in a range of cancers. Macrophages display intrinsic radio-resistance and radiotherapy can influence TAM recruitment and phenotype. However, whether radiotherapy alone can effective...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fonc.2022.1020606

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Publisher:
Frontiers Media
Journal:
Frontiers in Oncology More from this journal
Volume:
12
Article number:
1020606
Publication date:
2022-09-29
Acceptance date:
2022-09-12
DOI:
EISSN:
2234-943X
Pmid:
36249052
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1285620
Local pid:
pubs:1285620
Deposit date:
2022-11-06

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