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Journal article

Plasma protein biomarkers for the prediction of CSF amyloid and tau and [18F]-flutemetamol PET scan result

Abstract:
Background: Blood biomarkers may aid in recruitment to clinical trials of Alzheimer’s disease (AD) modifying therapeutics by triaging potential trials participants for amyloid positron emission tomography (PET) or cerebrospinal fluid (CSF) Aβ and tau tests. Objective: To discover a plasma proteomic signature associated with CSF and PET measures of AD pathology. Methods: Liquid chromatography-tandem mass spectrometry (LC-MS/MS) based proteom... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fnagi.2018.00409

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Role:
Author
Expand authors...
Alzheimer's Research UK More from this funder
GE Healthcare and Janssen Research and Development More from this funder
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Aging Neuroscience Journal website
Volume:
10
Article number:
409
Publication date:
2018-12-11
Acceptance date:
2018-11-28
DOI:
ISSN:
1663-4365
Source identifiers:
951510
Keywords:
Pubs id:
pubs:951510
UUID:
uuid:de43f1a4-816a-4c8f-a94b-e5673f645422
Local pid:
pubs:951510
Deposit date:
2018-12-11

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