Journal article
An integrated anti-arrhythmic target network of a Chinese medicine compound, Wenxin Keli, revealed by combined machine learning and molecular pathway analysis
- Abstract:
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Wenxin Keli (WK), a Chinese patent medicine, is known to be effective against cardiac arrhythmias and heart failure. Although a number of electrophysiological findings regarding its therapeutic effect have been reported, the active components and system-level characterizations of the component-target interactions of WK have yet to be elucidated. In the current study, we present the first report of a new protective effect of WK on suppressing anti-arrhythmic-agent-induced arrhythmias. In a mod...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 1.7MB)
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- Publisher copy:
- 10.1039/c7mb00003k
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Authors
Funding
Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- Molecular BioSystems Journal website
- Volume:
- 13
- Issue:
- 5
- Pages:
- 1018-1030
- Publication date:
- 2017-03-24
- Acceptance date:
- 2017-03-24
- DOI:
- EISSN:
-
1742-2051
- ISSN:
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1742-206X
- Pmid:
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28418441
- Source identifiers:
-
690319
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:690319
- UUID:
-
uuid:de41dbfd-bf1e-4de6-b68f-763f7a59d0ff
- Local pid:
- pubs:690319
- Deposit date:
- 2017-12-19
Terms of use
- Copyright holder:
- Wang et al
- Copyright date:
- 2017
- Notes:
- © the Author(s). This journal is © The Royal Society of Chemistry 2017. This is the accepted manuscript version of the article. The final version is available online from RSC at: 10.1039/c7mb00003k
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