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Targeting rheumatoid tenosynovial angiogenesis with cytokine inhibitors.

Abstract:

UNLABELLED: Proliferation and invasion of the tenosynovial lining of tendons in patients with rheumatoid arthritis can result in tendon damage and rupture, leading to decreased hand function. Angiogenesis is an important process in rheumatoid joint disease; however, the role of angiogenesis in tendon disease is unknown. Our aim was to determine whether rheumatoid tenosynovial lining could produce angiogenic proteins, and if inhibition of tumor necrosis factor-alpha and interleukin-1 could dec...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Brennan, F More by this author
Sandison, A More by this author
Paleolog, E More by this author
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Journal:
Clinical orthopaedics and related research
Volume:
446
Issue:
446
Pages:
268-277
Publication date:
2006-05-05
DOI:
EISSN:
1528-1132
ISSN:
0009-921X
URN:
uuid:ddf3728b-38d6-4754-a39a-c5c935b365fe
Source identifiers:
226628
Local pid:
pubs:226628

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