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Learning impairments of hippocampal-lesioned mice in a paddling pool.

Abstract:

Control mice rapidly learned to escape from shallow water in a paddling pool, which combined elements of the Morris water maze and the Barnes holeboard maze. The pool's transparent perimeter wall contained 12 exits, only 1 of which led to an escape tunnel. Learning was impaired in mice with cytotoxic lesions of the hippocampus. Probe trials suggested that the controls were using extramaze cues. When the exit was blocked, controls, but not hippocampals, spent more time searching in this previo...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Behavioral neuroscience
Volume:
116
Issue:
3
Pages:
472-478
Publication date:
2002-06-05
DOI:
EISSN:
1939-0084
ISSN:
0735-7044
URN:
uuid:ddf23a4c-9798-4b6c-a1b2-c2c95a03e8b0
Source identifiers:
24678
Local pid:
pubs:24678

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